Hyperinsulinism Due to Islet-cell Adenoma

بررسی تغییرات آسیب‌شناسی پانکراس در هیپوگلیسمی ناشی از افزایش انسولین در دوران نوزادی

Hyperinsulinism is responsible for about 55% of hypoglycemia in children less than 1 year old. In this study pancreas from 8 children with idiopathic hyperinsulinemic hypoglycemia of infancy(HHI) who underwent pancreatectomy in Ali-Asghar Hospital from 10 years ago were examined, using histochemical method and morphometric measurements. The children ranged from 3 to 13 months, and were ...

Effects of octreotide on circulating islet B cell products in endogenous hyperinsulinism.

The role of somatostatin analogues in the medical management of insulinomas is unclear. We describe an elderly patient with clinical and biochemical features of endogenous hyperinsulinism attributable to a benign islet B cell disorder whose incapacitating neuroglycopaenic symptoms responded dramatically to octreotide 50 micrograms subcutaneously at 2200 h each night. Octreotide suppressed inapp...

[Primary hyperaldosteronism due to adrenal adenoma].

Primary hyperparathyroidism due to parathyroid adenoma.

OBJECTIVE To evaluate the clinical characteristics and outcome of patients with parathyroid adenoma. METHODS We diagnosed and operated 54 patients with primary hyperparathyroidism in the Faculty of Medicine, Gazi University, Turkey from January 2000 to December 2004. In this study, 52 (96.2%) of these patients who had parathyroid adenoma were retrospectively evaluated. RESULTS There were 46...

Islet encapsulation: strategies to enhance islet cell functions.

Diabetes is one of the most prevalent, costly, and debilitating diseases in the world. Although traditional insulin therapy has alleviated the short-term effects, long-term complications are ubiquitous and harmful. For these reasons, alternative treatment options are being developed. This review investigates one appealing area: cell replacement using encapsulated islets. Encapsulation materials...